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Post# of 251813
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Re: jbog post# 42580

Wednesday, 02/28/2007 6:00:30 PM

Wednesday, February 28, 2007 6:00:30 PM

Post# of 251813
>>>A separate analysis of the satraplatin clinical trial handed out at the prostate cancer meeting this weekend broke down the drug's efficacy into the aforementioned individual components -- and revealed some worrisome details. On a percentage basis, more satraplatin patients "progressed" because of death, compared with patients in the control arm. And the only component listed above where satraplatin performed significantly better than the control arm was in the reduction of symptomatic pain.>>>

Has anyone here seen this separate analysis? What percentage of patients progressed because of death in each of the trial arms? If there was an imbalanced in overall survival against satraplatin, wouldn't the DSMB have stopped the trial? And, finally this seems like subset analysis, and I don't need to say anything more.

Dew -- are you negative on Satraplatin? and how does this fit in with your negativity?

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