Is it unexpected that a patient needing a lung transplant dies waiting?
How long can you wait for a lung transplant?
The average person waits around two years for a single lung transplant, and as long as three years for two lungs. People who are unable to wait that long may be considered for lung transplant from a living donor.
What organ transplant has the lowest success rate?
Lung transplant patients have the lowest 5- and 10-year survival rates, according to UNOS. “The lungs are a very difficult organ to transplant because they're exposed to the environment constantly as we breathe,” explained Dr. Steves Ring, Professor of Cardiovascular and Thoracic Surgery. Dr.Apr 26, 2017
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Pediatr Transplant
. 2015 May;19(3):294-300. doi: 10.1111/petr.12390. Epub 2014 Nov 19.
Lung transplant waitlist mortality: height as a predictor of poor outcomes
Britton C Keeshan 1, Joseph W Rossano, Nicole Beck, Rachel Hammond, James Kreindler, Thomas L Spray, Stephanie Fuller, Samuel Goldfarb
Affiliations expand
PMID: 25406495 DOI: 10.1111/petr.12390
Abstract
The LAS was designed to minimize pretransplant mortality while maximizing post-transplant outcome. Recipients <12 are not allocated lungs based on LAS. Waitlist mortality has decreased for those >12, but not <12, suggesting this population may be disadvantaged. To identify predictors of waitlist mortality, a retrospective analysis of the UNOS database was performed since implementation of the LAS. There were 16,973 patients listed for lung transplant in the United States; 12,070 (71.1%) were transplanted, and 2498 (14.7%) patients died or were removed from the wait list. Significantly more pediatric patients died or were removed compared with adults (22.0% vs. 14.4%, p < 0.01). In multivariate analysis, in addition to higher LAS at time of listing (adj. HR1.058, 1.055-1.060), shorter height (1.008, 1.006-1.010), male gender (1.210, 1.110-1.319), and requiring ECMO (1.613, 1.202-2.163) were associated with pretransplant mortality. Post-transplant survival was not affected by height. The current age cutoff may impose limitations within the current lung allocation system in the United States. Height is an independent predictor of waitlist mortality and may be a valuable factor for the development of a comprehensive lung allocation system.
Keywords: lung transplant; mortality; organ allocation; outcomes; pediatrics; waitlist.
© 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
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Comment in
Pursuing distributive justice in pediatric lung transplantation.
Mallory GB.
Pediatr Transplant. 2015 May;19(3):249-51. doi: 10.1111/petr.12434.
PMID: 25808911 No abstract available.
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Publication types
Research Support, U.S. Gov't, P.H.S.
MeSH terms
Adolescent
Body Height*
Body Weight
Child
Child, Preschool
Databases, Factual
Female
Humans
Infant
Infant, Newborn
Kaplan-Meier Estimate
Lung Diseases / mortality*
Lung Diseases / surgery*
Lung Transplantation*
Male
Multivariate Analysis
Retrospective Studies
Risk
Tissue and Organ Procurement
Treatment Outcome
United States
Waiting Lists*
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