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Re: DewDiligence post# 249864

Thursday, 11/30/2023 7:08:08 PM

Thursday, November 30, 2023 7:08:08 PM

Post# of 257323
I see the reduction as very decent considering the avg patient weighed around 225 lbs. I'll wait for the details to come out but I know the 24 week trial did not allow for dose adjustment. Every other trial allows this.

I think Alt made a big mistake not allowing adjustments as needed but if they're main goal was in dose finding I can see their point.

Altimmune (ALT) CEO Vipin Garg noted that the 15.6% mean weight loss with the 2.4 mg dose was associated with a mean weight loss of 32.2 lbs at 48 weeks and 48% of those on the 2.4 mg dose with baseline obesity no longer had obesity by the end of the study.

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