Yes; however, the HBs seroconverion makes an off-therapy relapse considerably less likely than merely having undetectable HBsAg at the end of treatment
Of the 11 with HBsAg loss, 6 participants...sustained HBsAg loss and remained anti-HBs positive for at least 24 weeks post-EOT. Among those who achieved HBsAg loss, anti-HBs titers > 500 mIU/mL at EOT predicted achieving sustained loss of HBsAg at 24 weeks post-EOT.