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Re: Biowatch post# 247633

Wednesday, 06/21/2023 2:42:50 PM

Wednesday, June 21, 2023 2:42:50 PM

Post# of 257313
Re: RVNC opportunity in cervical-dystonia and related disorders

What is estimated size of market?

Please see slide #29 in RVNC’s corporate slide set (https://investors.revance.com/static-files/3d765f7c-1d06-49ae-bac4-0fa4cf46a092 ), which shows 2022 market sizes for cervical dystonia ($470M worldwide, $325M US) and for spasticity ($822M worldwide, $654M US). These numbers can be expected to increase in 2023 and future years due to general market growth as well as the specific boost from the availability of a longer-acting toxin that doesn’t wear off between treatments (#msg-155833598).

Will RVNC charge premium price for [cervical dystonia and spasticity] patients?

For therapeutic indications, Daxxify will cost injectors roughly the amount per procedure as Botox. The reason there won’t be a material price premium for Daxxify in therapeutic indications (even though Daxxify carries a 10-40% price premium compared to Botox in aesthetic indications) is explained in #msg-172115594.

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