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DewDiligence

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Re: DewDiligence post# 244811

Wednesday, 01/25/2023 7:26:52 PM

Wednesday, January 25, 2023 7:26:52 PM

Post# of 257426
MGTA—(-24%/AH)—pauses_phase-1/2_trial_in AML/MDS after_patient_death deemed “possibly drug-related”:

https://finance.yahoo.com/news/magenta-therapeutics-voluntarily-pauses-mgta-210500940.html

Magenta Therapeutics today announced that the latest participant dosed at the Cohort 3 level (0.08 mg/kg) in the ongoing MGTA-117 Phase 1/2 Dose-Escalation Clinical Trial in relapsed/refractory acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) experienced a Grade 5 Serious Adverse Event (SAE) (respiratory failure and cardiac arrest resulting in death) deemed to be possibly related to MGTA-117.

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