>If you wanted to promote anticoagulation, you might think of partially inhibiting FVIII.<
This is exactly what BioInvent and ThromboGenics are trying to do with TB-402, but it’s a novel—and high-risk—approach. It’s tantamount to inducing a mild, artificial state of hemophilia-A while hoping to avert the major-bleeding events typical of more severe manifestations of the disorder.
“The efficient-market hypothesis may be the foremost piece of B.S. ever promulgated in any area of human knowledge!”