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donotknowityet

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donotknowityet

Re: iwfal post# 41608

Tuesday, 02/06/2007 5:24:46 PM

Tuesday, February 06, 2007 5:24:46 PM

Post# of 257275
Alexion results were encouraging and failed in the pivotal trials


Why did it happened? These were large double blind trials with low p values. Why is that (and that is not only Alexion) that you frequently have great double blind phase II and phase II results followed by a bomb in the pivotal trial?
Anybody has any good explanation?
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