Mymetics Corp (MYMX)

[Work Harder]

Indirect evidence that vaccine-induced antibodies can have adverse effects comes from a feline immunodeficiency virus (FIV) study, where cats were vaccinated with various recombinant envelope glycoproteins [46]. Although neutralization in cell-line based assays was observed in plasma samples from some vaccinated groups, no virus-neutralizing antibodies were detected in the feline lymphocyte assay. Upon FIV challenge, cell-associated FIV loads were increased in the groups vaccinated with recombinant FIV Env glycoproteins compared to other groups or controls. Passive transfer of unfractionated plasma from groups with increased cell-associated FIV enhanced viral infection parameters in the recipients. While these data imply ADE, an influence of other factor(s) present in unfractionated plasma cannot be ruled out.

That from second link

French Application No. 01 16290, December 17, 2001. novel peptides useful in the
treatment of FIV in cats, inventor Simone Giannecchini, Pending

https://www.sec.gov/Archives/edgar/data/927761/000095012803000464/j9927101exv10w38.txt

Simone Giannecchini

Retrovirus Center and Virology Section, Department of Experimental Pathology, University of Pisa, I-56127 Pisa,1 Department of Pharmaceutical Sciences, University of Salerno, I-84084 Fisciano, Italy,3 Mymetics Corporation, Annapolis, Maryland2

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC149492/

MRC (UK)

https://www.researchgate.net/publication/10879995_Antiviral_Activity_and_Conformational_Features_of_an_Octapeptide_Derived_from_the_Membrane-Proximal_Ectodomain_of_the_Feline_Immunodeficiency_Virus_Transmembrane_Glycoprotein

https://www.vet.cornell.edu/departments-centers-and-institutes/cornell-feline-health-center/health-information/feline-health-topics/feline-immunodeficiency-virus-fiv

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644647/