PRDS is leaning toward a 1400mg daily dose of PBI-0451 (two 350mg tablets BID, taken with food), according to the company’s presentation at CROI this week: https://ir.pardesbio.com/static-files/a8fa45a7-4cea-4827-a623-154c807c7372 (slide #19) 1400mg/day is a lot of drug, even for a short-course regimen.