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Re: NY1972 post# 20

Tuesday, 01/25/2022 7:07:22 PM

Tuesday, January 25, 2022 7:07:22 PM

Post# of 41
No, but the data its trained on is designed to distinguish tumour DNA from non-tumour DNA and clonal from sub-clonal neoantigens*. For any clonal sequences, they create peptides and use them for (patient-derived) DC co-culture, before T-cells (both CD4+ and CD8+) are added, reactivates are identified, and then selective expansion of them.

In 2H there will be additional low-dose mono data, higher-dose (Process 2) mono data, and combo data (plus Opdivo in melanoma, NSCLC is slightly behind).


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