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Re: iwfal post# 41409

Thursday, 02/01/2007 8:47:49 AM

Thursday, February 01, 2007 8:47:49 AM

Post# of 257269
One more note on MCU - it is without doubt true that the treated arm had substantially(!) worse death/stroke rate than placebo. My guess is probably p value under 0.20 THE WRONG WAY:

a) This is in line with the concern that MI as measured by CK-MB is perhaps not the best endpoint?

b) This explains why the company isn't talking numbers of patients but instead confining itself to p values and reductions.

Note that having the 'remainder group' be substantially the wrong way is a danger sign. Not the kiss of death, but not good.

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