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Re: jbog post# 240393

Thursday, 11/18/2021 5:31:26 PM

Thursday, November 18, 2021 5:31:26 PM

Post# of 257357
Re: ENTA EDP-721

Discontinuing a compound is always a letdown, but it’s much better to find a safety problem in phase-1 than later on.

ENTA will need to find a second oral compound to complement EDP-514 (the lead HBV compound), which could either be another RNA destabilizer or a compound with a different MoA. The company’s drug-discovery engine is up to the task, IMO.

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