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Re: sunspotter post# 383924

Friday, 11/12/2021 1:51:51 PM

Friday, November 12, 2021 1:51:51 PM

Post# of 405224
That fact check from Reuter's needs fact checked.

Vaccines that use mRNA technology are not gene therapy because they do not alter your genes, experts have told Reuters after contrary claims were posted online.



"Gene therapies" do not alter your DNA. Because mRNA vaccines don't alter your DNA does not mean that they are not gene therapy.

True, mRNA vaccines are non-integrating into our genome so they don't alter them. But they are gene therapies since they insert nucleotides to produce a protein in the host, the SARS2 spike protein.

"Gene editing" does alter DNA by removing base pairs, changing base pairs, or adding base pairs.

So mRNA vaccines are gene therapy, but they do not do gene editing or gene regulation.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7076378/

However, mRNA is often promulgated on the grounds of the popular opinion that when using mRNA, unlike DNA, the stringent gene-therapy regulations are bypassed because mRNA does not integrate into the host genome. However, in reality, this only holds true in the US since in Europe, any active pharmaceutical ingredient, which contains or consists of a recombinant nucleic acid, used in or administered to human beings, falls under the scope of the regulation for advanced therapy medicinal products [6]. Therefore, mRNA-based therapeutics are categorized as gene therapy.



As you would probably say to yourself, anybody who claims to be an expert that corrects other people should probably at least know a little bit of basic science and the difference between gene therapy, gene editing, and gene regulation.


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