As a pathologist I am not as comfortable with the apparent lack of changes in the frozen tissues sections as Mr. Stoll would seem to be. This process is not as sensitive as the paraffin-based histology and it is still possible that a real lesion is there. I am going to be more comfortable with negative electron microscopic findings and additional toxicology testing. I agree with your guesses about the FDA response (and I have continued to buy) but still I am a little nervous! Good luck to all.