Xenon Pharmaceuticals (XENE)

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Xenon Pharmaceuticals Reports Positive Phase 2b Result for Epilepsy Drug
7:21 am ET October 4, 2021 (Dow Jones) Print

By Matt Grossman


Xenon Pharmaceuticals Inc.'s XEN1101 drug achieved positive results in a Phase 2b trial studying its use as an adjunctive treatment for focal epilepsy, the company said Monday.

Compared with a placebo, the drug achieved a statistically significant reduction from the baseline in monthly focal seizure frequency, meeting the study's primary efficacy endpoint.

More than half of patients who received the highest dose of the medication studied experienced a greater-than-50% reduction in seizure frequency, Xenon said. At the median, participants had been experiencing a baseline level of 13.5 seizures per month before the study.

Xenon Chief Executive Ian Mortimer said that the results support an "attractive clinical profile" for the drug. Data from the study have also encouraged Xenon's plans to additionally develop the drug for the treatment of major depressive disorder and for other types of epilepsy, he said.


Write to Matt Grossman at [e-mail]


(END) Dow Jones Newswires

October 04, 2021 07:21 ET (11:21 GMT)

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