Assume a very conservative "20%." What is a Typical Profit Margin for Manufacturers? A typical manufacturer’s gross profit percentage falls between 25 and 35%. This is the gross margin, which reflects solely the relationship between revenue and the cost of goods sold. It does not include variables such as taxes, employee payments, and other ancillary expenses. https://www.verenia.com/cpq-configure-price-quote-blog/profit-margin-for-manufacturers-optimization