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Re: Paulness post# 44585

Thursday, 01/25/2007 11:38:58 PM

Thursday, January 25, 2007 11:38:58 PM

Post# of 64738
Endotoxins come from the fermentation process using e-coli, syn DNA does not use fermentation or e-coli so why the high % of endotoxins???

Annual report

The Company has also developed a novel technique for producing cell free plasmid
DNA thus] bypassing the fermentation process. The cell free synthesis of plasmid
DNA has numerous advantages: CytoGenix, synthetic DNA (SynDNA(TM)) is free of
the endotoxins,
bacteriAL DNA, RNA and proteins that must be laboriously removed
in the fermentation process using live bacteria. More importantly, synthetic DNA
can be produced more rapidly and less expensively than in the traditional
fermentation method.

CEO update

Continued improvements in the scaling up of the production of synDNA, an effort spearheaded by Drs. Michael Ma and Fredrick Kendirgi;
Purification of bacteria-free synDNA™ to eliminate all but 5% of impurities especially endotoxins, a critical step for the generation of large-volume sales and production of clinical grade material;





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