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Re: bio_guyo post# 3253

Thursday, 01/25/2007 5:59:04 PM

Thursday, January 25, 2007 5:59:04 PM

Post# of 4764
12-week response rate was not a standard endpoint used in oncology - therefore how predictive it will be of PFS and OS will be unknown.

Having said that, the added toxicity of triple may have shortened the treatment duration - and thus lower the chance for success in the future.

This is a medical affairs trial - so may not be respresentative of those in clinical development - which has trial program that essentially mimic the EPIC, the Crystal etc. Third-line rr seem to be rather comparable between the two drugs.

But the short-term threat is alleviated

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