Biotech Values

[DewDiligence]

AGN is back to the price where I shorted
it successfully last year. One reason is
optimism re the launch of the Juvederm
dermal filler. Below is a link to a set of
2.4x photos that purport to show that
Juvederm is a smoother product than
Restylane, the market-leading filler:
http://tinyurl.com/2dx5df . However,
this difference has little if any
clinical relevance, IMO.

http://biz.yahoo.com/bw/070117/20070117005319.html?.v=1

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Allergan, Inc. Announces Nationwide Availability of JUVEDERM™ ULTRA and JUVEDERM™ ULTRA PLUS Dermal Fillers

Wednesday January 17, 9:00 am ET

IRVINE, Calif.--(BUSINESS WIRE)--Allergan, Inc. (NYSE: AGN ), the maker of BOTOX® Cosmetic (Botulinum Toxin Type A), today announced nationwide availability of its 'next-generation' hyaluronic acid dermal filler family of products, JUVEDERM(TM) ULTRA and JUVEDERM(TM) ULTRA PLUS.

"We are pleased to now provide JUVEDERM(TM) dermal fillers to physicians and their patients across the country," said Robert Grant, President of Allergan Medical, a division of Allergan, Inc. "We believe that the unique scientific benefits and technologically advanced, smooth formulation of JUVEDERM(TM) will establish the brand as a leader alongside BOTOX® Cosmetic in Allergan's TOTAL FACIAL REJUVENATION(TM) offering."

The JUVEDERM(TM) dermal filler family of products provides physicians with the flexibility to tailor each treatment to a patient's particular needs. JUVEDERM(TM) ULTRA is a highly cross-linked formulation for more versatility in contouring and volumizing facial wrinkles and folds; and JUVEDERM(TM) ULTRA PLUS is a more highly cross-linked, robust formulation for volumizing and correction of deeper folds and wrinkles.

"In the clinical trials, I found JUVEDERM(TM) injectable gel to be a smooth-flowing product to inject, providing patients with a natural and smooth correction of facial wrinkles and folds," said Dr. Mark Pinsky, clinical investigator in the JUVEDERM(TM) dermal filler study. "I have seen similar results with the patients I have currently enrolled in the JUVEDERM(TM) Experience Trial, and I look forward to providing both JUVEDERM(TM) ULTRA and JUVEDERM(TM) ULTRA PLUS dermal fillers to many more of my patients now that the product is widely available. The ease of the injection and its long-lasting smooth and natural results make JUVEDERM(TM) an important facial rejuvenation tool in my practice."

JUVEDERM(TM) is the only hyaluronic acid dermal filler developed using the proprietary HYLACROSS(TM) technology, an advanced manufacturing process resulting in a malleable gel that flows easily into the skin and creates a smooth, natural look and feel. All other hyaluronic acid dermal fillers currently on the market, including Restylane® are granular consistency gels. An example of the granular consistency of Restylane® (under 2.4X magnification, 0.05 mL) can be seen in the accompanying photo and can be compared to JUVEDERM(TM) ULTRA and JUVEDERM(TM) ULTRA PLUS (under 2.4X magnification, 0.05 mL). The clinical significance of the differences has not been established.

Physicians and consumers are encouraged to visit www.Juvederm.com to receive additional information about JUVEDERM(TM) ULTRA and JUVEDERM(TM) ULTRA PLUS dermal fillers. The Web site also offers a physician locator to help consumers find a trained and qualified health care provider in their area.

About Allergan Medical

Allergan Medical, a division of Allergan, Inc., offers the most comprehensive, science-based, aesthetic product offerings under its TOTAL FACIAL REJUVENATION(TM) portfolio, including BOTOX® Cosmetic; hyaluronic acid and collagen-based dermal fillers; and physician-dispensed skin care products. Allergan Medical also offers the industry's widest range of silicone gel-filled and saline-filled breast implant options for reconstructive and aesthetic breast surgery, and leading minimally invasive devices for obesity intervention treatment.
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