"We will be able to provide additional updates and information as we learn more."
Koepka is currently 12th in the Official World Golf Ranking. The 30-year-old finished in a tie for second place at the World Golf Championships-Workday Championship at The Concession on Feb. 28.
Kopeka will be replaced in the 154-player field at The Players Championship by Anirban Lahiri of India, provided a player not otherwise exempt wins the Arnold Palmer Invitational.
The Players Championship begins Thursday at TPC Sawgrass in Ponte Vedra Beach, Fla.