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Re: jbog post# 237204

Monday, 02/22/2021 7:00:01 PM

Monday, February 22, 2021 7:00:01 PM

Post# of 257288
Re: RVNC /upper-limb spasticity

It took the highest (500mg) dose to come in with a .048 statsig number. Don't know how this will fare in a [phase-3 trial].

The effect size (and duration of effect) seems to be consistent with what RVNC was expecting, although the actual numeric value hasn’t yet been disclosed (pending presentation at a medical conference). The p-value in the 500mg cohort would presumably have looked better if the trial had enrolled 128 patients, as planned, instead of the actual 83 patients due to COVID.

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