Wednesday, February 03, 2021 10:22:50 AM
@bio
( I was typing when you posted )
----
So the knowable information is, along those lines, ...
794 test and control patients
-298 events
===============================
496 living (of 794)
The auxiliary arm, 928 - 794 = 134 patients we know nothing about (yet)
62.47% of the total population of test and control (794) is still alive. (when 298 events occurred)
That was AT pretty much 3 years (or longer) for all enrolled
Crudely 1/3rd at 5yr+, 1/3rd at 4yr, 1/3rd at 3 year.
=======================================================================
Now, what happens is there is a crude expectation if you just look at raw numbers, how many enrolled.
The whole thing DOES automatically SLIDE forward in time if you look at the Monthly Enrollment (quite a bit)
"Took 2 years longer than expected" - take with a small grain of salt, that is a complicated statement when you factor the monthly enrollment.
I would have to go back and jump through hoops again, but back of the napkin, about a year.
We recover the drama though if we ponder how significant an effectivness in the test arm has to be if the SOC arm matches literature and does not fluke high.
( I was typing when you posted )
----
So the knowable information is, along those lines, ...
794 test and control patients
-298 events
===============================
496 living (of 794)
The auxiliary arm, 928 - 794 = 134 patients we know nothing about (yet)
62.47% of the total population of test and control (794) is still alive. (when 298 events occurred)
That was AT pretty much 3 years (or longer) for all enrolled
Crudely 1/3rd at 5yr+, 1/3rd at 4yr, 1/3rd at 3 year.
=======================================================================
Now, what happens is there is a crude expectation if you just look at raw numbers, how many enrolled.
The whole thing DOES automatically SLIDE forward in time if you look at the Monthly Enrollment (quite a bit)
"Took 2 years longer than expected" - take with a small grain of salt, that is a complicated statement when you factor the monthly enrollment.
I would have to go back and jump through hoops again, but back of the napkin, about a year.
We recover the drama though if we ponder how significant an effectivness in the test arm has to be if the SOC arm matches literature and does not fluke high.
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