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Monday, November 16, 2020 2:34:40 PM
medRxiv
. 2020 Sep 18;2020.09.16.20190694. doi: 10.1101/2020.09.16.20190694. Preprint
We report that Kidney Injury Molecule-1/T cell immunoglobulin mucin domain 1 (KIM-1/TIM-1) is expressed in lung and kidney epithelial cells in COVID-19 patients and is a receptor for SARS-CoV-2. Human and mouse lung and kidney epithelial cells express KIM-1 and endocytose nanoparticles displaying the SARS-CoV-2 spike protein (virosomes).
Brigham and Women's Hospital, Harvard Medical School
https://www.medrxiv.org/content/10.1101/2020.09.16.20190694v1
https://pubmed.ncbi.nlm.nih.gov/32995803/
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