Saturday, October 24, 2020 3:40:19 PM
Peripherally Administered Nanoparticles Target Monocytic Myeloid Cells, Secondary Lymphoid Organs and Tumors in Mice
Toon Stegmann
Jeffrey A. Hubbell
Melody A. Swartz
This study was partly funded by Carigest SA. Toon Stegmann is employed by Mymetics BV. The EPFL has filed for patent protection on the nano particles described. There are no further patents products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.
Contributed reagents/materials/analysis tools: ICK SH AdT TS
Funding: This study was funded by the Bill and Melinda Gates Foundation (to JAH and MAS), Carigest SA (to MAS), Oncosuisse (to MAS), and the European Research Council project NanoImmune (to JAH). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
All chemicals were reagent grade and purchased from Sigma-Aldrich (Saint Louis, MO) unless otherwise noted. Antibodies for flow cytometry were purchased from eBioscience (San Diego, CA)
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0061646
clone BM8, diluted 1/66; eBioscience, catalogue number 25-4801-82
(clone LN3 diluted 1/50; eBiosciences catalogue number 47995642)
https://www.nature.com/articles/s41541-020-0190-9
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=158994802
CARIGEST SA
Council in Geneva, Switzerland
Rue de l'Athénée 24, 1206 Genève, Switzerland
http://www.carigest.ch/
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=158830753
https://www.google.com/maps/dir/La+Maison+de+l'Horlogerie+SA,+Rue+du+Cendrier+24,+1201+Gen%C3%A8ve,+Switzerland/CARIGEST+SA,+Rue+de+l'Ath%C3%A9n%C3%A9e+24,+1206+Gen%C3%A8ve,+Switzerland/@46.2015414,6.1417012,16z/data=!3m1!4b1!4m13!4m12!1m5!1m1!1s0x478c6599ebfc0bbb:0x7debaa4ae7c6ca5b!2m2!1d6.1454277!2d46.2074682!1m5!1m1!1s0x478c7acd1a7aad6b:0x4154735795896be6!2m2!1d6.1525705!2d46.1955375
Yah, I'd say Texas Pete knows a thing or two
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=159066231
I bet Toon & team never sleeps as well
Furthermore, the particles are in liquid form and do not require refrigeration, making this vaccination methodology easily applicable in the developing world.
LOL
Toon Stegmann
Jeffrey A. Hubbell
Melody A. Swartz
This study was partly funded by Carigest SA. Toon Stegmann is employed by Mymetics BV. The EPFL has filed for patent protection on the nano particles described. There are no further patents products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.
Contributed reagents/materials/analysis tools: ICK SH AdT TS
Funding: This study was funded by the Bill and Melinda Gates Foundation (to JAH and MAS), Carigest SA (to MAS), Oncosuisse (to MAS), and the European Research Council project NanoImmune (to JAH). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
All chemicals were reagent grade and purchased from Sigma-Aldrich (Saint Louis, MO) unless otherwise noted. Antibodies for flow cytometry were purchased from eBioscience (San Diego, CA)
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0061646
clone BM8, diluted 1/66; eBioscience, catalogue number 25-4801-82
(clone LN3 diluted 1/50; eBiosciences catalogue number 47995642)
https://www.nature.com/articles/s41541-020-0190-9
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=158994802
CARIGEST SA
Council in Geneva, Switzerland
Rue de l'Athénée 24, 1206 Genève, Switzerland
http://www.carigest.ch/
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=158830753
https://www.google.com/maps/dir/La+Maison+de+l'Horlogerie+SA,+Rue+du+Cendrier+24,+1201+Gen%C3%A8ve,+Switzerland/CARIGEST+SA,+Rue+de+l'Ath%C3%A9n%C3%A9e+24,+1206+Gen%C3%A8ve,+Switzerland/@46.2015414,6.1417012,16z/data=!3m1!4b1!4m13!4m12!1m5!1m1!1s0x478c6599ebfc0bbb:0x7debaa4ae7c6ca5b!2m2!1d6.1454277!2d46.2074682!1m5!1m1!1s0x478c7acd1a7aad6b:0x4154735795896be6!2m2!1d6.1525705!2d46.1955375
Yah, I'd say Texas Pete knows a thing or two
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=159066231
I bet Toon & team never sleeps as well
Furthermore, the particles are in liquid form and do not require refrigeration, making this vaccination methodology easily applicable in the developing world.
LOL
