<This is what happened with GENR, and you know the rest of that story.>
I was fortunate enough to get out of GENR more than a year ago prior to the release of their phase 2 results and the sound of the bell. Luckily I never traded it at a loss.
I also got out of COR long ago and SNUS recently, Cramer calling Sonus a 9$ stock would make sense if they reach superiority, but I find too hard to call and heading out seems safer as the reaction could be unpredictable if they get non-inferiority.
I also got out of EPIX with some loss, it seems a crapshoot at this point in spite of its partnership and because of the uncertainty regarding the funding of trials (They just announced an IPO though previous CCs had said their current cash would be sufficient for 2 years..doesnt sound good to me. They also refuse to say whether their partner will fund any trials..wow.). I traded these shares for PANC which I had been following with one eye for a year but never bought before, the current price seems fair in spite of the delays they expect(the last CC seemed honest in predicting a 12mths delay, worse case, and a 3mnths delay, best case).