Mymetics Corp (MYMX)

[Work Harder]

Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody

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Daniel Douek

https://www.pnas.org/content/117/31/18754

https://relationshipscience.com/person/ruth-ruprecht-27409841

or other Fc-mediated antibody effector functions54, and synergies among IgG and IgA toward gp41 and/or gp120 can offer better virus inhibition and protection50,55. The reported conserved epitopes on gp41 make this viral protein another very attractive antigen that could be included in prophylactic HIV-1 vaccines for establishing front-line defenses at the primary mucosal entry point used by HIV-1 to prevent virus transmission, local infection, and dissemination

https://www.nature.com/articles/s41541-020-0190-9

Competing Interests

The authors have read the journal's policy and declare the following potential competing interests: KEB was employed by a commercial company, Inovio Pharmaceuticals, Inc. and ML was employed by BioQual, Inc. This does not alter our adherence to PLOS ONE policies on sharing data and materials. There are no patents, products in development or marketed products to declare.

https://journals.plos.org/plosone/article/authors?id=10.1371/journal.pone.0228163