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Tuesday, July 21, 2020 4:11:32 PM
Actually,
Placebo Arm, 28 patients:
6 patients reported a total of 11 SAE's, altogether
Drug Arm, 56 patients:
5 patients reported a total of 8 SAE's, altogether (none related to Leronlimab)
Obviously, some patients reported more than one SAE.
To reach equivalency between 28 patients vs. 56 patients, I suppose you could simply multiply the placebo arm numbers by a factor of 2 therefore, theorizing 12 patients in placebo arm reporting a total of 22 SAE's. .
The total of SAE's by the entire group=22 theoretical placebo plus 8 actual for drug = 30 total SAE's for both arms.
Then: Placebo = 22/30 or 73% Drug = 8/30 or 26%
So out of total SAE's the placebo group experienced 73% of total SAE's in the trial and Leronlimab group experienced 26% of the total reported SAE's. Thus, control arm experienced 2.8 times as many Serious Adverse Effects.
There's my creative analysis. We don't know how many of the SAE's were related to having Covid-19, and we'll find this out soon, I'm sure.
Placebo Arm, 28 patients:
6 patients reported a total of 11 SAE's, altogether
Drug Arm, 56 patients:
5 patients reported a total of 8 SAE's, altogether (none related to Leronlimab)
Obviously, some patients reported more than one SAE.
To reach equivalency between 28 patients vs. 56 patients, I suppose you could simply multiply the placebo arm numbers by a factor of 2 therefore, theorizing 12 patients in placebo arm reporting a total of 22 SAE's. .
The total of SAE's by the entire group=22 theoretical placebo plus 8 actual for drug = 30 total SAE's for both arms.
Then: Placebo = 22/30 or 73% Drug = 8/30 or 26%
So out of total SAE's the placebo group experienced 73% of total SAE's in the trial and Leronlimab group experienced 26% of the total reported SAE's. Thus, control arm experienced 2.8 times as many Serious Adverse Effects.
There's my creative analysis. We don't know how many of the SAE's were related to having Covid-19, and we'll find this out soon, I'm sure.
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