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Re: knrorrel post# 4660

Sunday, 07/12/2020 10:59:30 AM

Sunday, July 12, 2020 10:59:30 AM

Post# of 6035
We got a winner here right place right time.



@HeatBiologics
"The elderly & those...suffering most...from this pandemic should know they do not need to settle for a 1-size-fits-all solution. We are working to bring...vaccine options to help those at greatest risk." CEO Jeff Wolf on the need for a "super-vaccine": http://bit.ly/2NRvlV3


#ICYMI, Jeff Wolf's thoughts on #COVID-19: "While Congress and the Administration weigh a new funding package to respond to COVID-19, they should keep in mind the special needs of America’s seniors and other immune-compromised high-risk communities": http://bit.ly/2NRvlV3

• Multiple grants received to utilize gp96 platform for various
infectious diseases
- National Institute of Health (NIH)
- Department of Defense (DoD)
- Florida Department of Health
• Heat Biologics leverages the body

Key Differentiation of gp96 Platform:


NO ANTI-VECTOR IMMUNITY ?
NO VIRAL ACTIVATION ?
NO INTEGRATION OF FOREIGN DNA ?
INTO HOST GENOME ?
ACTIVATION OF T CELLS ?
ACTIVATION OF B CELLS ?
HIGH IMMUNOGENICITY ?
INDUCTION OF MUCOSAL IMMUNITY ?
LONG-TERM MEMORY RESPONSE ?


• Leverages our proprietary gp96
platform to effectively deliver multiple
SARS-CoV-2 antigens to activate the
immune system.

Designed to elicit long-lasting immune
response against SARS-CoV-2 virus

We plan to collaborate with companies,
researchers, government agencies and
funding organizations to accelerate our
COVID-19 vaccine program.


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PTX-35 TNFRSF25
(mAb Solid Tumors is a billion dollar plus drug in the making
Phase 1 fully funded by grants


HS-110-NSCLC indication gp96 + CTAs
(Cell Therapy Nearing Phase 3


HS-130 OX40L solid tumors indication Nearing Phase 2


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Heat Biologics and University of Miami Developing Proprietary COVID-19 Diagnostic Test Under Collaborative Research Agreement
https://www.heatbio.com/news-media/news-releases/detail/652/heat-biologics-and-university-of-miami-developing

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Heat Biologics Announces Formation of COVID-19 Advisory Board

https://www.heatbio.com/news-media/news-releases/detail/654/heat-biologics-announces-formation-of-covid-19-advisory

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Heat Biologics Invited to Join The Alliance for Biosecurity

https://www.heatbio.com/news-media/news-releases/detail/651/heat-biologics-invited-to-join-the-alliance-for-biosecurity

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Heat Biologics Announces Collaboration with Waisman Biomanufacturing to Manufacture COVID-19 Vaccine.
https://www.heatbio.com/news-media/news-releases/detail/659/heat-biologics-announces-collaboration-with-waisman

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Heat Biologics Reports Progress on COVID-19 Efforts and Timeline of Anticipated Q2 2020 Milestones:

https://www.heatbio.com/news-media/news-releases/detail/655/heat-biologics-reports-progress-on-covid-19-efforts-and


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