Biotech Values

[DewDiligence]

Re: HBV addendum

The Evaluate Vantage write-up linked in the immediately preceding post may have a science error:

…hep B is a relatively intractable virus, and the thinking is that to achieve a functional cure viral DNA and HBsAg must both be suppressed to prevent rebound infections. The virus also persists in a reservoir of cccDNA, but this alone is not thought capable of reviving infection.

I have not seen anything to support this assertion regarding cccDNA.