HCQ and Chloroquine MOA. The below linked paper (found by biomaven) is easily the best putative chloroquine MOA paper. The authors went out of their way to duplicate the results using a very different ‘drug’ but with same MOA. And then ruled out various other ways in which the pair of drugs could have the observed effect.
Note: quinine, like the two drugs used in the paper, is also a lysosomotropic agent.
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