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Wednesday, March 18, 2020 5:30:21 PM
Good video, thanks.
Testing, testing, testing, testing... PCR NAT (Nucleic Acid Testing).
In early 2000s I invented a technology for multiplex NAT that is more sensitive and better than PCR, and then started a company based on this technology that was recently valued at more than $1.2B ($NSTG). However, the nanostring technology is not suitable for Covid-19, it's strength is in testing multiple nucleic acids simultaneously, the virus is too simple of a target for such a sophisticated technology.
After nanostring I spent years on a new technology that would be much faster, cheaper and simpler than nanostring: perfectly suitable for Covid-19. It's a platform technology, could work on every bug, but since Covid was not known then, the first target I wanted to develop a test for was malaria. Got money from Bill Gates to do that. Got patents and proof-of-principle data. In the meantime, while working on it, I came up with the Fibrilyzer and Matrilyzer concept, so I focused on these two and the "malaria" technology" was left behind at a pre-prototype stage.
Here's the funny story I am getting to: the original patents for the "malaria" tests were also licensed to $EXDI, together with Fibrilyzer and Matrilyzer, as a long-term project. Would have been perfect now, if it was developed: highly accurate and sensitive test within minutes. It's a pity...
Testing, testing, testing, testing... PCR NAT (Nucleic Acid Testing).
In early 2000s I invented a technology for multiplex NAT that is more sensitive and better than PCR, and then started a company based on this technology that was recently valued at more than $1.2B ($NSTG). However, the nanostring technology is not suitable for Covid-19, it's strength is in testing multiple nucleic acids simultaneously, the virus is too simple of a target for such a sophisticated technology.
After nanostring I spent years on a new technology that would be much faster, cheaper and simpler than nanostring: perfectly suitable for Covid-19. It's a platform technology, could work on every bug, but since Covid was not known then, the first target I wanted to develop a test for was malaria. Got money from Bill Gates to do that. Got patents and proof-of-principle data. In the meantime, while working on it, I came up with the Fibrilyzer and Matrilyzer concept, so I focused on these two and the "malaria" technology" was left behind at a pre-prototype stage.
Here's the funny story I am getting to: the original patents for the "malaria" tests were also licensed to $EXDI, together with Fibrilyzer and Matrilyzer, as a long-term project. Would have been perfect now, if it was developed: highly accurate and sensitive test within minutes. It's a pity...
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