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Post# of 252412
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Alias Born 01/22/2006

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Sunday, 12/10/2006 2:07:01 PM

Sunday, December 10, 2006 2:07:01 PM

Post# of 252412
HCV treatment question

Was just making notes for the InterMune BMO call and looking at some of the Vertex data from an article or two and had a thought (perhaps others are way ahead of me and have ruled it out completely or considered it). Anyway 191 so far as shown to have strong potency for the resistant variants of 950. Granted it is not proven in humans yet and there are lot of things that could show up but I was wondering if things progress along these lines would a treatment regimen without a PEG (and possibly Ribavirin as well) be possible (i.e. using combo PI's and perhaps Polymerase Inhibitors)? Or are there other reasons you'd want to keep using an Interferon? TIA


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