Anavex Life Sciences Corp (AVXL)

[XenaLives]

Compiled: GUT and BRAIN 09/29/19
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Gut Microbiome Interactions with Drug Metabolism, Efficacy and Toxicity, excerpt:
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=150720420

The Future of Medicine Lives in Your Gut(from raja48185)
https://www.popularmechanics.com/science/health/a27309621/biotech-microbiome/

Secret to longevity may lie in the microbiome and the gut:(from raja48185)
https://www.sciencedaily.com/releases/2018/05/180531114611.htm

Homeostasis in the gut
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=150387327
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=150387203

from the AAIC July 14 - 18, 2019 presentation entitled
Exploring Gut Microbiota as a Source of Potential Biomarkers
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=150387830

AAIC Gut Brain slide show
https://www.anavex.com/wp-content/uploads/2019/07/Anavex-Microbiota-Presentation-AAIC-July-2019-1.pdf
The PR from the company:
https://www.globenewswire.com/news-release/2019/07/17/1884144/0/en/Anavex-Life-Sciences-Presents-New-Clinical-Data-Identifying-Gut-Microbiota-Biomarkers-Associated-with-Improved-Clinical-Response-in-Patients-Treated-with-ANAVEX-2-73-at-2019-Alzhei.html
Comments on the above presentation:
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=149974727
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=149978044
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=149985216
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=149985666
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=149989886
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=149991264
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=150006346
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=150007211
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=150007389
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https://investorshub.advfn.com/boards/read_msg.aspx?message_id=150009238
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=150010055
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=150011341
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=150012367

Ruminococcaceae - a big subject which I know little but here's a starter..
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=149999945
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=150010584

The AD microbiome study referenced in the Anavex presentation.
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=149985216

Research does suggest the gut-brain-axis is bidirectional.
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=150172419

Gut/Parkinson’s/mitochondria (from Biostockclub)
https://www.nature.com/articles/d41586-019-02094-6

Boosting a gut bacterium helps mice fight an ALS-like disease
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=150058256

A Walnut-Enriched Diet Affects Gut Microbiome in Healthy Caucasian Subjects:
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=149987857

Microbiome mind and brain interaction

Glysophate uptake through foods may cause increase in autism and other conditions affecting Mitochondria through Clostridium overgrowth in the gut: (from Investor2014)

Gut Microbiota in Alzheimer’s Disease, Depression, and Type 2 Diabetes Mellitus: The Role of Oxidative Stress
(from nidan7500)
https://www.hindawi.com/journals/omcl/2019/4730539/

Vitamin D, Deep sleep & Gut Bacteria w/ Dr. Stasha Gominak (from Investor2014)

Parkinson’s may originate in the gut, mentions misfolded protien. Several articles and comments in 6/19
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=149595187
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=149617947
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=149618008
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=149620533
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=149646371

Alzheimer's Disease and the Gut Microbiome, three videos from georgejjl
https://www.youtube.com/watch?v=2H60C8_NF-0
https://www.youtube.com/watch?v=wXFUVXpVoaM
https://www.youtube.com/watch?v=7ZBhQxrrv84

On the importance of the Microbiome:
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=149748710

The Brain-Gut-Microbiome Axis (from nidan7500)
https://www.cmghjournal.org/article/S2352-345X(18)30060-2/fulltext

Gut bacteria may change the way many drugs work in the body ew research could help doctors choose medications for patients based on their microbiota
BY MARIA TEMMING 11:00AM, JUNE 3, 2019 (from kevli33)
https://www.sciencenews.org/article/gut-bacteria-may-change-way-many-drugs-work-body

Gut microbiota in Parkinson's disease: Temporal stability and relations to disease progression. (from georgejjl)
https://www.ncbi.nlm.nih.gov/pubmed/31221587


Gut microbes eat our medication (from kevli33)
https://www.sciencedaily.com/releases/2019/06/190613143629.htm


Rett Syndrome: A Focus on Gut Microbiota. (from georgejjl)
An important read
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343879/

EPIGRAPH VOL. 21 ISSUE 3, SUMMER 2019
Microbiome research in epilepsy: Hope or hype? (from kevli33)
https://www.ilae.org/journals/epigraph/epigraph-vol-21-issue-3-summer-2019/microbiome-research-in-epilepsy-hope-or-hype

What we do and don't know about gut health (from raja45185)
http://www.bbc.com/future/story/20190121-what-we-do-and-dont-know-about-gut-health

Understanding The Microbiome, Erica Sonnenburg, PhD
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=148374722

New 'interspecies communication' strategy between gut bacteria and mammalian hosts uncovered (from MycroftHolmes)
https://m.phys.org/news/2019-02-interspecies-strategy-gut-bacteria-mammalian.html

Gut brain in canine model:
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=148871706
Comment on the above:
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=148871841

Absent Aß, Blood-Brain Barrier Breakdown Predicts Cognitive Impairment (From Investor2014)
https://www.alzforum.org/news/research-news/absent-av-blood-brain-barrier-breakdown-predicts-cognitive-impairment

Beginning of 1/21/19 discussion on new BBB research:
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=146238086

Gut Brain connection
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=146262229

AVXL 2-73 and cerebral blood flow:
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=143582952

Dr. Tanzi on infection and Alzheimer's, also "soda brain".
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=143979877

Restoration of gut microbiota as MOA in a possibly competitive Chinese compound:
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=144442713

XenaLives posts on gut/brain:
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=144443836
https://investorshub.advfn.com/boards/read_msg.aspx?message_id=144443854

Microbiome testing going from the research lab into the clinic (from kevli33)
https://individualizedmedicineblog.mayoclinic.org/2019/04/02/purna-kashyap-m-b-b-s-testing-the-bugs-within-to-maintain-health-detect-and-treat-disease