GTC Biotherapeutics (fka GTCB)

[DewDiligence]

Recombinant Factor VIIa in Massive Postpartum Hemorrhage

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&l...

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Int J Obstet Anesth. 2006 Nov 22.

Karalapillai D, Popham P.

Department of Anaesthesia, Royal Women's Hospital, Carlton, Victoria, Australia.

Massive postpartum haemorrhage is a major cause of maternal and fetal morbidity and mortality. Management mainstays include transfusion therapy, uterotonic agents and surgery. The "off label" use of recombinant activated factor VII appears to have an evolving role in the management of massive postpartum haemorrhage refractory to conventional treatments. The current literature is reviewed.
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