Tuesday, May 28, 2019 1:47:07 PM
On point 2: this is an encouraging early sign, and it tracks with about what I expected to see as far as efficacy. Tumor cell infiltration by immune cells, an early correlate that SOMETHING is going on.
The big sticker is whether observations of stable disease is going to be enough. Obviously, if you can keep a patient's cancer stable, then you've technically turned it into a chronic disease. However, in traditional therapy, stable disease generally signals that treatment has not worked, or that it is about to stop working.
Therefore, I don't view "stable disease" results as inherently negative, especially with immunotherapy. But ADXS is definitely going to have its work cut out for it when it comes to convincing others that something meaningful is going on, since they're not seeing bona fide responses (which is not surprising for a phase 1 study).
Recent ADXS News
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 03/06/2024 12:13:01 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 03/05/2024 09:30:45 PM
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- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 11/21/2023 02:04:41 PM
- Form SC 13D/A - General statement of acquisition of beneficial ownership: [Amend] • Edgar (US Regulatory) • 11/21/2023 02:00:50 PM
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- Form 3/A - Initial statement of beneficial ownership of securities: [Amend] • Edgar (US Regulatory) • 11/03/2023 03:45:26 PM
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- Form SC 13D/A - General statement of acquisition of beneficial ownership: [Amend] • Edgar (US Regulatory) • 10/31/2023 11:05:10 AM
- Form SC 13G/A - Statement of acquisition of beneficial ownership by individuals: [Amend] • Edgar (US Regulatory) • 10/23/2023 10:45:21 AM
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