Mymetics Corp (MYMX)

[bow-tie]

Going a little further:
The (International) American Society of Tropical Medicine and Hygiene
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094245/

Updated Feb/March 2017

Active/Pre-Clinical
DNA / ChAd63 (encoding CS, AMA1, or ME-TRAP ) in prime-boost regimen changed start of Phase 1b clinical trial to 2017
Inactive/Clinical
NMRC-M3V-Ad-PfCA updated references
moved to pre-erythrocytic vaccine

NMRC-M3V-D/Ad- PfCA Prime/Boost updated references
moved to pre-erythrocytic vaccine

PATH/MVI

Active/Pre-Clinical
DNA / ChAd63 (encoding CS, AMA1, or ME-TRAP ) in prime-boost regimen new project added

Active/Clinical
RTS,S-AS01 delayed fractional third dose new trials added

Inactive/Clinical
RTS,S/AS01E Reference added

RTS,S/AS01B + ChAd63 and MVA encoding ME-TRAP Reference updated


WRAIR
Active/Pre-Clinical
SAPN nanoparticle P. falciparum CSP Adjuvant added
Updated storage temperature
Phase 1a start date updated

Recombinant P. falciparum CSP Description of product updated
Preclinical and Phase 1a dates added



EVI

Active/Pre-Clinical
PAMVAC Removed (only clinical activity remaining)

Active/Clinical
pfAMA1-DiCo Notes updated

P27A Notes updated

PAMVAC Study completion date updated
Reference added

ChAd63/MVA ME-TRAP Reference corrected

R21/AS01B Study completion dates updated

R21/Matrix-M1 Notes updated
Study completion dates updated
doses received updated

adjuv R21 (RTS,S-biosimilar) with ME-TRAP combined Trial Registration No included
Time schedule updated
doses received updated
Country/date for phase 2a added

PRIMVAC Phase 1b studay start date uupdated
Reference added
Cooperating partner added

ChAd63 Pfs25-IMX313/MVA Pfs25-IMX313 Study completion dates updated


EDCTP
Active/Clinical
ChAd63/MVA ME-TRAP updated notes
references added

R21/Matrix-M1 Phase1b trial information added

P27A updated notes

NIH/NIAID
Active/Pre-Clinical
PfSPZ GM1 (genetically knockout) New Project added

EBA175/GLA-LSQ New Project added

AMA-1/RON2/GLA-SE New Project added

live PvSPZ New Project added

Recombinant P. vivax CS Protein-based Vaccine Moved to Inactive/Preclinical

RH5 Moved to Inactive/Preclinical

EBA175/Rh5 Combination Vaccine Moved to Inactive/Preclinical

Active/Clinical PfSPZ Vaccine description of product updated
notes updated

Pfs25-EPA/Alhydrogel comments added

Pfs230D1M-EPA/Alhydrogel and/or Pfs25-EPA/Alhydrogel comments added

Pfs230D1M-EPA/Alhydrogel and Pfs25-EPA/AS01 comments added
clinicaltrials.gov number added

PfSPZ-CVac (PfSPZ Challenge + chloroquine or + chloroquine/pyrimethamine Comments added
Study completion date added

GAP 3KO (52-/36-/sap1-) P. falciparum sporozoites New project added

February 2017 Update - World Health Organization
www.who.int/immunization/research/development/Rainbow_table_detailed.xlsx
22, Naval Medical Research Center (Navy Component, US Military Malaria Vaccine Program) (USA). 23, GenVec ..... 105, London School of Hygiene and Tropical Medicine, UK. 106, Makerere ...... 234, Mymetics Corporation. 235, Phase Ib: ...
www.who.int/immunization/research/development/Rainbow_table_detailed.xls
x

CSP, AMA1 virosomes (PEV 301,302) Phase Ia: NCT00400101 Swiss Tropical Institute Swiss Tropical Institute (Switzerland) Switzerland X X X Virosomal AMA-1 and CS mimotopes P. falciparum D0, D90 50µg of AMA1 virosome (PEV 301), 10µg of CS virosome (PEV 302) i.m. Switzerland Tanzania Genton 2007 PLoS One
Mymetics Corporation
Phase Ib: NCT00513669 Pevion Biotech Ltd a/b Okitsu 2007 PLoS One
Bagamoyo Research and Training Unit (Tanzania) Tanzania
Ifakara Health Research Development Centre, (Tanzania)

Information Source
ID Number: PMAL03
NCT Identifier: NCT00513669
Record on Clinical Trials.gov:http//clinicaltrials.gov/show/NCT00513669
Processed March 12th 2019

https://trialbulletin.com/lib/entry/ct-00513669