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Re: gofishmarko post# 37171

Friday, 11/10/2006 3:30:32 PM

Friday, November 10, 2006 3:30:32 PM

Post# of 257273
i have a funny feeling the dose used was not reflective of pharmacological dosing in human trials
i am not a pharmacologist, and don;t knwo how animal dosing translates to human, but it appears that concentrations were used that are comparable with 500 mg PER KG daily doses of nm-283 (i assume this was because idix had published on comparable doses from their pre-clinical studies). as we know 200-800 mg/DAY are given clinically
just a thought/guess

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