Aren't the changes in design supposed to be refrected here: https://clinicaltrials.gov/ct2/history/NCT03132675?A=8&B=9&C=merged#StudyPageTop ? On a separate note: I wonder why they were not stressing the point that the subjects on the study were those who had already failed every other treatment. It certainly was a talking point at the previous conference call. Not that it made any difference in terms of pps, but anyway...
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