Sunday, December 09, 2018 8:53:09 PM
The FDA approval was after reviewing previous clinical trial history.
I suspect your doctor is confusing host defense peptides with host defense peptide mimetics. Brilacidin is a host defense peptide mimetic.
http://www.ipharminc.com/brilacidin-1/
Regarding toxicity of Brilacidin with systemic use you should read the following paper. Or, at least, the section on Brilacidin starting on page 8.
Mimics of Host Defense Proteins; Strategies for Translation to Therapeutic Applications
by Richard W. Scott*,1 and Gregory N. Tew2
In Current Topics in Medicinal Chemistry, 2017, 17, 576-589
https://static1.squarespace.com/static/5715352e20c647639137f992/t/59c41c8ed2b857d4a753fa6b/1506024591539/Tew-CurrTopMedChem-2017-2017-review+with+Rick+Scott.pdf
Btw, I have to say I'm quite thankful for Sunday urgent care. I can't count the times I've visited them on a weekend over the years. Whether for myself or my kids.
In Reply to 'Jewelsoftheworld'
I just got out of my doctors for sinus infection. I am on the last antibiotic that works for me. I asked him about Brilacidin and he was familiar with the drug. His remarks were that we may not get that one because it’s having safety issues in the trials because it’s damaging the liver and failing enzyme tests. Does anyone know if this is true? Maybe he was confusing it with another trial? Maybe it’s not that big a deal? Can anyone with better medical research skills check on this and see if it’s accurate?
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