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Re: poorgradstudent post# 36525

Monday, 10/30/2006 1:07:26 PM

Monday, October 30, 2006 1:07:26 PM

Post# of 257268
re : CK elevation

It seems to be a characteristic of the nukes :

"A variety of clinical symptoms such as myopathy, polyneuropathy, lactic acidosis, liver steatosis, pancreatitis, and lipodystrophy have been identified in human immunodeficiency virus (HIV)-infected patients treated with antiretroviral therapy containing one or more nucleoside reverse transcriptase inhibitors (NRTIs) (6, 34). Some of these adverse effects, which usually occur after prolonged treatment, are linked to mitochondrial toxicity, as demonstrated in a number of in vitro and in vivo studies with various NRTIs."

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