Friday, August 24, 2018 1:52:15 PM
VDB
I agree with your monetary assessments, but want to clarify something. CVSI WILL SUCCEED with phase 1. I've been around pharma, so what we're waiting for is for them to file their IND. Last year they had a meeting with FDA and learned some valuable things. So they are now doing the analytical work and animal work and making sure they can reliably manufacture different doses of this to go with the nicotine gum. No small feat. When they get that done and file the IND, they will also include a protocol for the phase 1 study. Normally, Phase 1 is with healthy volunteers (i.e., non chewers), but in the best of all worlds, they would have access to chewers. They'll look at at least 2 doses of the drug/gum combination vs placebo (no CBD). They make sure they can measure blood levels and urine levels in a reliable fashion. At the end of that, they'll have valuable information about picking a dose (or two) for the Phase II study, in which they will definitely go into tobacco chewers. In this phase, they'll get a good idea about how well it works (efficacy) and the safety profile. My guess is after a successful phase 1 trial, someone will try to acquire them. And how bloody smart is CVSI that it can fund predominantly on the consumer sales. So people should chill for a year. They're killing it in sales and will continue to go up. The drug development program is continuing. Hang in there and don't sweat day to day variations. I look at SP multiple times a day, but that doesn't change my resolve. Confident that this is the stock of my lifetime. Have a great WE all.
MT
I agree with your monetary assessments, but want to clarify something. CVSI WILL SUCCEED with phase 1. I've been around pharma, so what we're waiting for is for them to file their IND. Last year they had a meeting with FDA and learned some valuable things. So they are now doing the analytical work and animal work and making sure they can reliably manufacture different doses of this to go with the nicotine gum. No small feat. When they get that done and file the IND, they will also include a protocol for the phase 1 study. Normally, Phase 1 is with healthy volunteers (i.e., non chewers), but in the best of all worlds, they would have access to chewers. They'll look at at least 2 doses of the drug/gum combination vs placebo (no CBD). They make sure they can measure blood levels and urine levels in a reliable fashion. At the end of that, they'll have valuable information about picking a dose (or two) for the Phase II study, in which they will definitely go into tobacco chewers. In this phase, they'll get a good idea about how well it works (efficacy) and the safety profile. My guess is after a successful phase 1 trial, someone will try to acquire them. And how bloody smart is CVSI that it can fund predominantly on the consumer sales. So people should chill for a year. They're killing it in sales and will continue to go up. The drug development program is continuing. Hang in there and don't sweat day to day variations. I look at SP multiple times a day, but that doesn't change my resolve. Confident that this is the stock of my lifetime. Have a great WE all.
MT
Recent CVSI News
- Form 10-K - Annual report [Section 13 and 15(d), not S-K Item 405] • Edgar (US Regulatory) • 03/26/2026 09:14:16 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 03/26/2026 08:06:03 PM
- CV Sciences, Inc. Reports Fiscal Year-End 2025 Financial Results • ACCESS Newswire • 03/26/2026 08:00:00 PM
- CV Sciences, Inc. To Announce Year End and Fourth Quarter 2025 Results On March 26, 2026 • ACCESS Newswire • 03/24/2026 09:00:00 PM
- CV Sciences Announces Successful Debt Restructuring Designed to Strengthen Financial Position and Fuel Future Growth • ACCESS Newswire • 03/10/2026 09:00:00 PM
- CV Sciences Launches EMPOWR: A Plant-Based Protein + Creatine Formula Designed for Total Wellness • ACCESS Newswire • 02/26/2026 01:30:00 PM
- CV Sciences, Inc. Positioned to Participate in the Medicare and Medicaid Pilot Program for CBD • ACCESS Newswire • 12/23/2025 12:00:00 AM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 11/13/2025 10:19:06 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 11/13/2025 09:04:08 PM
- CV Sciences, Inc. Reports Third Quarter 2025 Financial Results • ACCESS Newswire • 11/13/2025 09:00:00 PM
- CV Sciences, Inc. to Announce Third Quarter 2025 Results on November 13, 2025 • ACCESS Newswire • 11/10/2025 11:15:00 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/10/2025 09:05:25 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 09/18/2025 08:24:23 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 08/13/2025 09:23:14 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 08/13/2025 08:01:09 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 05/14/2025 08:50:18 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 05/14/2025 08:01:33 PM
- Form DEF 14A - Other definitive proxy statements • Edgar (US Regulatory) • 04/15/2025 09:25:41 PM
