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Re: mcbio post# 219768

Saturday, 06/23/2018 7:19:41 PM

Saturday, June 23, 2018 7:19:41 PM

Post# of 251809

ASMB—Obviously, if the true rate of decay ends up being several years, then that's a different story.

The problem, as I see it: The method ASMB used to estimate the half-life of cccDNA decay has such a wide confidence interval that it might actually take several years (if it can be done at all) for cccDNA to be eradicated once viral replication has been shut down.

It's good for humanity that somebody is testing to see if a short course of DAA treatment can cure HBV; however, I question whether this is an enterprising pursuit from an investment standpoint.

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