With respect I'll disagree re " logically immaterial to your decision to hold "
There will always be known unknowns as well as unknown unknowns around a decision to buy a stock. If I'm buying the stock I feel I have researched it enough / followed it enough to understand its business plan , its execution of that plan and know its delta re general market movements.
So having gone thru that ground work I know that I will not know everything but will have a range I can live with. If it drops below that range ( ie down 20% for example ) I conclude theres something I've missed and re evaluate my position .