Cytodyn Inc (CYDY)

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small numbers of non-responders

Yes, with success measured not just a drop in viral load but by 0.5log reduction.

Primary Outcome Measures:

Proportion of participants with ≥ 0.5 log10 reduction in HIV-1 RNA viral load from baseline at the end of the 1-week double-blind treatment period

Inclusion: Plasma HIV-1 RNA ≥ 400 copies/mL

So someone with a viral load of 400, log 400= 2.602. A 0.5log reduction would be 2.102 or 126 to be counted as a success for PE, with just one dose.