Innovation Pharmaceuticals Inc (IPIX)

[PlentyParanoid]

Great find KMBJN. Thanks. Most subjects HPV+ positive. Virus is driving the cancer -
That is treatment friendly!!!!! Faster recovery, shorter SOM durations. This was pointed out on critique of Kepivance trials for SOM in head and neck cancer back 2012. One reason why Amgen probably canned the idea to go to FDA for expansion of indication for Kepivance. If the same is true for P2 trial then it is getting hairier and hairier with GALERA's GC4419. Meaning, only gods know what the big time H. is going on.

Well, meaningfulness of median and averages depends on what is reported. SOM trials report (when the bother) duration median against intent to treat population, which becomes silly if you don't have events to hit 50 %. Median will be zero. Also, median does not tell you the distribution shape. People tend to assume that it is exponential. In case of SOM it is anything but. Average does not tell you shape, either. But it tells you what is the area under the distribution curve. That is always useful.

The thing is a bit different if median is reported only for subjects experiencing SOM. Then it has meaning (even to me).