Soxski, the three times a week was at 1/3 the earlier dose so they were looking to prove what BP wanted to know is did it show up in tumor and affect p53 etc.....they are not looking for tumor shrinkage in this setup...however we will see as in safty studies there appears to have been some exciting results in shrinkage of tumors anyway.....when they up doses or do them everyday then we will see shrinkage !and thanks again for all your updates, lots of work on your part we can all see..