shears, "uptodate" is a subscription service...basically an online Physicians Desk Reference. It is the cliff notes that all doctors use every day.
"While waiting for the conference call to begin, in case anyone wants some clinical background on Factor VIIa, I took this from NowUpToDate, a subscription medical resource, so no link provided. Note the reference to 92% off label use. Also, the cost is astounding for the existing recombinant product."