Biotech Values

[Whalatane]

Titan. I read a P1 trial for VK2809 ...56 patients with mild hyper cholesterol.
Of these 56 ...10 of them developed asymptomatic elevations of Liver enzymes ...mostly elevated ALT at the higher doses .
Elevated ALT levels indicate that the Liver cells are inflamed and damaged with the risk over time ,of losing function .
IMHO its very unlikely this drug will ever be used by Hetero Familia Hypercholestremia patients as most of us are on high intensity statins and vulnerable to elevated ALT levels already.

This is not a comment on VKTX's potential for treating NASH .
I'm not an MD so those on this board who are , might have a different view.

MGL-3196 is the best drug I've seen in development so far for Hetero FH patients ....when possibly used with Statins ,and Zetia as an alternative to PCSK9's ( which are generally limited to only the very high risk patients )
JMO
Kiwi