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Re: biotech jim post# 215728

Wednesday, 12/06/2017 10:17:38 AM

Wednesday, December 06, 2017 10:17:38 AM

Post# of 257458
MDGL. ..Biotech Jim ...Thx for initiating the discussion on MDGL several days ago .
Next up I think is data on Hetero FH ...Mid Jan ?
Can you post some thoughts on this trial ?

I'm hetero FH ...LDL cholesterol over 300 without Statins . Elevated liver enzymes are a risk for many Hetro FH patients as it takes max dose Statins to have any real effect on lowering LDL ....even then best we can often do is to cut our LDL levels in half ...maybe lower with Zetia added ...BUT still end up with LDL over 100 .

PCSK9's ..expensive and a lot of payer resistance .

MDGL's drug looks to have benefit on multiple levels ...appreciate your thoughts on the Hetero FH trial

thx
Kiwi

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